Rotimürgi (kolekaltsiferooli) Toksilisus Hobustel

2024 Autor: Daisy Haig | [email protected]. Viimati modifitseeritud: 2023-12-17 03:07

Kolekaltsiferooli mürgitamine hobustel

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Kolikaltsiferool (D3-vitamiin) on mitut tüüpi rotimürgi toimeaine. Kolikaltsiferooli suur annus põhjustab kaltsiumi destabiliseerumist organismis, mis põhjustab hüperkaltseemia seisundit ja lõpuks keha kudede ja elundite lupjumist. Suurenenud kaltsiumisisaldus veres põhjustab tõsiseid neerukahjustusi.

Mõnikord puutuvad hobused kokku kolikaltsiferooliga saastunud hobusesöödaga, võib-olla siis, kui mürk on ladustamisaladesse pandud ja seetõttu tahtmatult mürgitatud. See juhtub sageli ilma hooldaja teadmata. Selle ühendi võib alla neelata ka siis, kui sööt on valesti segatud või valmistatud või kui D3-vitamiini toidulisand on liiga innukas.

Sümptomid

• Söögiisu kaotus (anoreksia)
• Kaalulangus
• Depressioon
• Hingamisraskused (düspnoe)
• Liigne janu (polüdipsia) koos suurema veetarbimisega
• Suurenenud uriini tootmine (polüuuria)
• Nõrkus
• Suurenenud pulss
• Jäseme jäikus
• Rahu
• Surm

Põhjused

• Kolikaltsiferooli allaneelamine, tavaliselt tahtmatult
• Tavaliselt hõlmab toidu saastumist rotimürgiga

Diagnoos

Teie veterinaararst saab diagnoosida kolikaltsiferooli toksilisust, esitades vereproovi laborisse, mis mõõdab ühendi taset seerumis. Tavapärasem veretöö näitab fosfori ja kaltsiumi kõrgenenud taset ning neerukahjustuse märke.

Ravi

Kolialtsiferooli mürgituse ravi varieerub igal üksikjuhul eraldi, sõltuvalt allaneelatud mürgi kogusest ja sümptomite raskusastmest.

Kõige tavalisem lähenemisviis ravile on tavaliselt seotud toidu ja toidulisandite kaudu vastuvõetava D-vitamiini koguse piiramisega. Võib anda kaltsiumkelaatori, kuna see vähendab kaltsiumi imendumist soolestikus. Ravi tuleb alustada ka neerupuudulikkuse korral. See on tavaliselt toetav ravi ja nõuab suures koguses IV vedeliku manustamist.

Elamine ja juhtimine

Sellest toksikoosist taastumine võib olla pikk ja sageli tasumatu, kuna kudede lupjumist ja neerupuudulikkust ei saa tagasi pöörata. Prognoosi valvatakse ja sageli valitakse eutanaasia.

Ärahoidmine

Kuigi juhuslikku allaneelamist ei ole võimalik vältida, tekib aeg-ajalt seda tüüpi toksikoos vitamiinipreparaatide vale haldamise kaudu. Enne kui alustate hobuse lisaravimist, arutage seda oma veterinaararstiga.